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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX10
All Species:
25.15
Human Site:
S557
Identified Species:
42.56
UniProt:
Q13206
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13206
NP_004389.2
875
100888
S557
A
Y
F
N
E
K
M
S
I
L
Q
K
G
G
K
Chimpanzee
Pan troglodytes
XP_001141618
875
100804
S557
A
Y
F
N
E
K
M
S
I
L
Q
K
G
G
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536583
871
100167
S558
A
Y
F
N
E
K
M
S
I
L
Q
K
G
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y44
875
100720
S558
A
Y
V
S
E
K
M
S
V
L
H
K
S
G
E
Rat
Rattus norvegicus
NP_001100290
874
101001
S558
A
Y
F
S
E
K
M
S
I
L
H
K
S
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509692
859
98483
S559
A
Q
F
S
E
K
M
S
L
L
Q
R
G
G
K
Chicken
Gallus gallus
Q5ZJF6
875
100138
S566
I
N
P
S
G
K
L
S
V
N
R
S
K
E
E
Frog
Xenopus laevis
NP_001089088
663
75544
T411
Y
I
H
R
V
G
R
T
A
R
Y
K
E
G
G
Zebra Danio
Brachydanio rerio
XP_001922220
864
99178
S555
L
Q
Q
Q
K
T
K
S
E
P
S
Q
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573230
826
92827
Q550
Q
L
Q
Q
Q
K
E
Q
G
D
N
A
K
S
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780056
867
98194
D551
N
E
R
T
L
H
E
D
S
Q
R
D
E
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FFT9
739
83563
D487
R
S
I
H
K
R
R
D
K
E
I
F
D
V
S
Baker's Yeast
Sacchar. cerevisiae
P20448
770
87174
A511
K
N
A
P
R
Q
L
A
F
L
S
K
A
N
E
Red Bread Mold
Neurospora crassa
Q7RZ35
823
92654
D543
K
E
V
R
T
K
Y
D
K
M
A
E
R
Q
N
Conservation
Percent
Protein Identity:
100
99
N.A.
89
N.A.
85.1
86.2
N.A.
73.1
66.8
54.1
59.6
N.A.
42.2
N.A.
N.A.
48.4
Protein Similarity:
100
99.7
N.A.
94.2
N.A.
92.4
93.1
N.A.
84
79.6
64.2
76.5
N.A.
62.2
N.A.
N.A.
68.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
60
80
N.A.
73.3
13.3
13.3
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
80
86.6
N.A.
93.3
46.6
20
26.6
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.9
38.7
40.2
Protein Similarity:
N.A.
N.A.
N.A.
57.6
56.9
57.7
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
8
0
0
0
0
8
8
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
22
0
8
0
8
8
0
0
% D
% Glu:
0
15
0
0
43
0
15
0
8
8
0
8
15
15
29
% E
% Phe:
0
0
36
0
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
8
8
0
0
8
0
0
0
29
50
8
% G
% His:
0
0
8
8
0
8
0
0
0
0
15
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
0
29
0
8
0
0
0
8
% I
% Lys:
15
0
0
0
15
65
8
0
15
0
0
50
15
0
29
% K
% Leu:
8
8
0
0
8
0
15
0
8
50
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
43
0
0
8
0
0
0
0
0
% M
% Asn:
8
15
0
22
0
0
0
0
0
8
8
0
0
8
8
% N
% Pro:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
15
15
15
8
8
0
8
0
8
29
8
0
8
0
% Q
% Arg:
8
0
8
15
8
8
15
0
0
8
15
8
8
8
15
% R
% Ser:
0
8
0
29
0
0
0
58
8
0
15
8
22
8
8
% S
% Thr:
0
0
0
8
8
8
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
15
0
8
0
0
0
15
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
36
0
0
0
0
8
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _